The study “Cannabinoid Exposure During Pregnancy: Consequences for Growth, Memory and Prefrontal Cortex Integrity in Wistar Rats” (Suleiman et al., 2025) explores the effects of prenatal exposure to THC and CBD—the active compounds in cannabis—on fetal development. The findings reveal that even late-pregnancy exposure led to significantly lower birth weights, structural brain changes in the prefrontal cortex, and memory impairments in offspring. These effects were consistent across THC-only, CBD-only, and combined exposure groups, indicating neurodevelopmental risks regardless of cannabis form.
This research adds to the growing body of evidence suggesting that cannabis use during pregnancy, often considered harmless by the public, can have lasting impacts on cognitive and behavioral development. The study provides compelling preclinical data to support the message that cannabis is not a risk-free substance during pregnancy.
Reflection: Integrating This Research into FASD Prevention Training
This study provides strong evidence that cannabis use during pregnancy—whether THC or CBD—can impact fetal brain development and long-term cognitive outcomes. FASD Prevention Facilitators can use this research to strengthen training across sectors by:
• Reinforcing that cannabis is not a safe alternative during pregnancy and highlighting the neurodevelopmental risks associated with its use. (Clarifying risk)
• Equipping professionals with non-judgmental, evidence-based language to discuss cannabis use with clients and patients. (Supporting informed conversations)
• Helping educators, health, and social service providers recognize the potential developmental effects of prenatal cannabis exposure, even in the absence of alcohol use. (Cross-sector awareness).